ea0099ep441 | Thyroid | ECE2024
de Carlos Joaquin
, Zabalza Lucia
, Irigaray Ana
, Rosario Aznarez Maria
, Oquinena Susana
, Pineda Arribas Javier
, Anda Apinariz Emma
Introduction: MUTYH (MutY homolog Escherichia coli, homolog of MYH, hMYH) is a repair enzyme with a crucial role in the correction of DNA errors, being considered a protective factor of the cell. MUTYH mutations have been linked to MUTYH-associated polyposis syndrome (MAP), an autosomal recessive disorder characterized by multiple colorectal adenomas. Patients with MAP show a much higher lifetime risk of gastrointestinal cancers as an additional role of MUTYH, it appears to co...